In addition to the main Core Set 2021 expansion, Wizards of the Coast will release a supplemental Jumpstart set on July 17.
This set will include a reprint of Exquisite Blood, an enchantment from the Avacyn Restored set. It synergizes perfectly with Vito, Thorn of the Dusk Rose, a new card from Core Set 2021.
This lethal combo will be huge in commander and eternal formats, such as legacy and vintage, which drives up the prices on Vito, Thorn of the Dusk Rose. However, don't expect prices to go too high; Vito, Thorn of the Dusk Rose will have no impact on standard or pioneer.