There is something very special going on when the main character ditches his signature weapons just to wail on his least favorite villain with his bare hands. That's the time when the hero decides to express his loathing in a very personal and intimate way. And there is no better way to do that than a good-old fashioned punch to the face.
But Kratos was always a "go big or go home" kind of guy. In this case, "home" is "the depths of Hades" and "big" is "punch the King of the Gods in the face until you're blinded by his blood and grey matter".
He does this on top of Mount Olympus, during the apocalypse, and after brutalizing through virtually every other god and demigod on earth. Except for Aphrodite, whom he had sex with right before impaling her husband with his own blacksmithing equipment. But I would not call any of those other boss fights manly (except for boning Aphrodite, because that's worth bragging about). THIS fight was the manliest because a mortal man decided to take the kill-everything swords off and beat in the skull of Zeus himself with nothing but his fists.
What do you think? What are the manliest moments in video games?