Back when Alien: Isolation was leaked, it was listed as an Xbox Live game with up to four-player multiplayer. This was the original element that interested some gamers, as the potential there is quite intriguing. While we've seen plenty bombastic Alien Versus Predator multiplayer, we have yet to see a subdued, Damned-style Alien multiplayer experience.
In future Alien: Isolation games, Creative Assembly should really consider testing multiplayer. Co-op was apparently briefly tested, but promptly dropped. What if, instead of co-op, we took the game's highly praised survival mode, and take it to the furthest extreme. What if we make one to three players survivors, who have to achieve goals, whilst another player controls a xenomorph alien - perhaps a little bit similar to Evolve.
Players would need to remain stealthy, and extremely clever. This would be the ultimate test of skill for many players, and every death of a teammate would intensify each players' terror drastically. You could still use your flamethrower to deter the xenomorph, but it will do little more than require it retreat for a time before spawning in a new vent. Your resources, unlike its respawns, would also be limited and would require searching the level.
The best part of this is that the xenomorph would be genuinely unpredictable. Maybe the player controlling the xenomorph is overly aggressive and can be easily avoided due to lack of finesse on their part. Or the xenomorph player decides to toy with players, sneaking up on them when they least expect it, and leaving little hint of its presence.
So as a result, we get the cooperative experience that Alien: Isolation could have had, but also get a competitive multiplayer that touches directly on what makes Alien: Isolation such a great horror game. I, for one, hope we see something like that with whatever Alien: Isolation 2 turns out to be.