This sultry, sexy, and over-the-top gun-slinging babe is perhaps one of the most controversially discussed females in gaming. Why? Because even feminists can't seem to decide if she's a derogatory or empowering character.
While I'll leave that debate to someone else, I will say that Bayonetta certainly earns a #2 spot on this list. Having saved the world from apocalyptic destruction on more than one account, our little "Cherry" is one of the most lethal women in this list. With the powers of Hell at her disposal, Bayonetta has taken on - not one - but two gods, multiple archangels, several archdemons, and Rodin (basically Satan himself) in her short career.
Bayonetta's arsenal is nothing to scoff at either. If you thought dual-wielding guns was impressive, Bayonetta quad-wields a series of swords, pistols, flamethrowers, and rocket launchers. On top of that she has the ability to summon archdemons at will. While she is technically the hero of her series, she tends to be just as destructive as her opponents. Bayonetta has destroyed planes, airfields, skyscrapers, towns, cities, and more without much effort at all.
But there's always a bigger fish. That leaves us with the #1 gun-gal on our list...