War and Death have their own games, but Strife is left out. Is that fair? And he isn't the only one.
Strife (second in from the left) is known for his excellent marksmanship. He wields two pistols, Mercy and Redemption.
This could allow for an expanding on the shooting mechanics employed by the current games to a more 3rd person style, for only the shooting. However, if this game become a third person shooter that would be pretty disastrous, but just using the mechanics.
The game could be based on stylistic shooting, employing a Matrix style bullet time and diving mechanics, maybe even wall running mixed with the standard Darksiders abilities and melee.