The new Mishra card can be either a commander or find its way into your 99. Either way it will do well!
There is currently a solid combo with this card that combines Mishra, Tamer of Mak Fawa, Void Maw, and Composite Golem (or Myr Battlesphere). You need to put either Composite Golem or Myr Battlesphere into your graveyard, and have Mishra and Void Maw stay on board. You also need to have at least three mana available, including black and red mana.
As a result, you can get an infinite amount of tokens and mana, so try it out.