Throughout the Deus Ex series, we play as a character with superhuman abilities at the cost of some of his humanity. In Deus Ex: Human Revolution our main character, Adam Jensen, is the survivor of an attack that killed his girlfriend. His survival came at the price of having the majority of his body augmented with cybernetics and robotics.
Throughout the game, you see just how much of an impact the modification of our bodies with cybernetics has divided the people. The shadowy mega corporations that work behind the scenes use their influence to sow discord, and skew the population's perception on the topic of transhumanism.