There are a lot of little Diablo references in the game.
For example, the above Diableaux hot sauce poster, which is found in Route 66.
There's also a check nearby signed by Deckard Cain. If you haven't played the Diablo games, Cain was a smart old guy that helps you save the world.
There's also a Diablo reference in Dorado. You know all those little piñatas? They're little Diablos.
Too bad the real Lord of Destruction isn't full of candy. It would've been nice to have a snack after saving the world.