How to Beat the Apocalyptic Guide in Persona 5
The Apocalyptic Guide is the last mini boss in Persona 5, fought right before you fight the final boss. He's the fourth and final angel you fight in the area who brings together the strongest attacks from the other three. It's a tough fight, but if you're prepared he's much easier to defeat.
In this short guide, I'm going to go over the best strategies for facing this formidable enemy and bringing him down effectively.
Defeating the Apocalyptic Guide in Persona 5
The Apocalyptic Guide will usually start his first turn by summoning two Zealous Messengers. These guys will spend their turns buffing or healing him, so you should focus them when they appear and get rid of them as soon as you can. Any skill that targets all enemies will be helpful here -- especially insta-kill curse skills.
The boss himself gets two actions per turn, which allows him to do some insane combos like charge (double attack buff) and sword dance (colossal physical damage to a single target). These combos can pretty much one shot Joker if you aren't prepared. The Guide has many strong moves that deal status effects and debuff your party -- including Megadolan, which deals severe almighty damage to your whole party.
The Apocalyptic Guide has no weakness and he drains light, but he's susceptible to critical hits -- much moreso than the other 3 mini-bosses before him. So the best party to have will contain a lot of physical attackers.
Make sure you have Fox and Skull with some moves that have higher crit chance, like Luck Punch or Miracle Punch. Queen would probably be good as well, to have another physical attacker but also one that can heal. If you don't want to go with Queen, then Noir's One-Shot Kill (severe gun damage, high crit rate) can also be a good option.
As for Joker's persona, anyone with physical move, high crit moves would be best. Seth knows One-Shot Kill, so he'd be very strong here. Considering the Guide's wide range of moves, you can't really plan to have a persona that resists/blocks/absorbs any one element in order to counter him. So it's best to focus on dealing as much damage as possible in short amounts of time so that you can bring him down faster rather than using survivability to extend the fight.
Following these steps it should be very easy to take down the Apocalyptic Guide, as long as you aren't vastly under-leveled. He has a lot of health, but don't let that intimidate you. Just pile on the damage and you should be alright.
Hope this helps! For more tips and tricks to get you through the game, check out the rest of our Persona 5 guides here on GameSkinny.